منابع مشابه
Mutations of ESPN cause autosomal recessive deafness and vestibular dysfunction.
We mapped a human deafness locus DFNB36 to chromosome 1p36.3 in two consanguineous families segregating recessively inherited deafness and vestibular areflexia. This phenotype co-segregates with either of two frameshift mutations, 1988delAGAG and 2469delGTCA, in ESPN, which encodes a calcium-insensitive actin-bundling protein called espin. A recessive mutation of ESPN is known to cause hearing ...
متن کاملSudden deafness
The author explains the clinical presentation, pathophysiology, diagnostic work-up, and management of sudden deafness. "Sudden" deafness is defined as sensorineural hearing loss of 30 decibels or more in at least 3 contiguous frequencies occurring over less than 3 days. The pathophysiology of sudden deafness is poorly understood. Various theories have been proposed, including those attributing ...
متن کاملCochlear and Vestibular Functional Study in Patients with Sudden Deafness and Lyme Disease
Lyme disease (LD) and idiopathic sudden deafness (ISD) are supposed to be different diseases with different aetiologies. In an attempt to confirm this assumption, 10 patients with confirmed LD and 12 patients with ISD were consecutively included into the study. Further to the laboratory and audio logical investigation, a low frequency sound (LFS) stimulation on posturography was performed and e...
متن کاملComplement activation in sudden deafness.
OBJECTIVE To test whether complement activation is associated with sudden deafness. DESIGN Plasma samples obtained from patients in the acute phase of sudden deafness were analyzed for complement activation measured by C3bc levels and terminal complement complex. Comparisons were made with plasma samples from healthy controls. PATIENTS Twenty-five adult patients with unilateral sudden deafn...
متن کامل[Sound therapy in sudden deafness].
INTRODUCTION AND GOALS Idiopathic sudden sensorineural hearing loss is a hearing disorder of unknown cause. The spontaneous recovery rate ranges from 50 to 75% of the patients. Scientific experiments on animals support the present study in patients with sudden deafness treated with sounds. PATIENTS AND METHODS During the period 2003-2009, patients with idiopathic sudden sensorineural hearing ...
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ژورنال
عنوان ژورنال: Equilibrium Research
سال: 2000
ISSN: 0385-5716,1882-577X
DOI: 10.3757/jser.59.277